measles during arbovirus outbreak: a diagnostic challenge

an interesting article by doctors at ​centre hospitalier territorial de nouvelle-calédonie dengue fever is a major public health problem in new caledonia, like in many pacific islands countries and territories. in 2017 new caledonia faced multiple circulations of arboviruses with a major outbreak of dengue and a co-circulating zika virus. new caledonia is considered as a non-endemic territory for measles since the mid 1990’s. a 41-year-old … Continue reading measles during arbovirus outbreak: a diagnostic challenge

500 miles against suicide; 500 miles against fear

yesterday i biked from my home in jamaica plain to the massachusetts medical society (mms) for a meeting, and then back to waltham center where I took the commuter rail home. with wrong turns, it was about 20 miles, much of it on sidewalks and up and down hills, in the oppressive 90 degree heat. i was almost hit by a car turning right once, … Continue reading 500 miles against suicide; 500 miles against fear

ibalizumab for multidrug-resistant hiv-1

and now, a fascinating new study published in the new england journal of medicine entitled phase 3 study of ibalizumab for multidrug-resistant hiv-1.  ibalizumab, a humanized igg4 monoclonal antibody, blocks the entry of hiv-1 by noncompetitive binding to cd4. besides the obvious issues of cost and long-term safety outcomes, i wonder about the why the study was 25 weeks long. why not 26 weeks or 50 … Continue reading ibalizumab for multidrug-resistant hiv-1

brilliant work by marjorie pritchard and ellen clegg

in my opinion, marjorie pritchard and ellen clegg at the boston globe are doing brilliant work with their campaign, ‘journalists are not the enemy.’ “i choose my friends for their good looks, my acquaintances for their good characters, and my enemies for their intellects. A man cannot be too careful in the choice of his enemies.” — oscar wilde what do you think? please leave a … Continue reading brilliant work by marjorie pritchard and ellen clegg