Check out this article in the Journal of Infectious Diseases by Derron Alves et al. A rhesus macaque monkey had necrotizing scleritis, conjunctivitis, peri-optic neuritis, and choriomeningoencephalitis 18 days after being challenged with the Ebola virus and apparently recovering. The animal had to be euthanized.
A few questions that come to mind:
- How good is the macaque model for representing human disease?
- Why did Dr. Ian Crozier survive Ebola and not relapse like this monkey did?
- Might this animal have eventually cleared the virus or progressed to death?
- How often and where does Ebola lurk in the bodies of people who have apparently recovered/survived (in the eye, the semen, etc)?
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