Ebola in the Rhesus Macaque

Check out this article in the Journal of Infectious Diseases by Derron Alves et al. A rhesus macaque monkey had necrotizing scleritis, conjunctivitis, peri-optic neuritis, and choriomeningoencephalitis 18 days after being challenged with the Ebola virus and apparently recovering. The animal had to be euthanized.

A few questions that come to mind:

  • How good is the macaque model for representing human disease?
  • Why did Dr. Ian Crozier survive Ebola and not relapse like this monkey did?
  • Might this animal have eventually cleared the virus or progressed to death?
  • How often and where does Ebola lurk in the bodies of people who have apparently recovered/survived (in the eye, the semen, etc)?

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Thanks so much for visiting my website! Writing and reading blog posts does take time and we all know that time is in short supply. You and I will both get much more out of this blog if it leads to dialogue. If you found my post useful and wouldn’t mind leaving a brief comment or sharing on social media, I would be grateful. Or if you’re shy about Tweeting but are willing to email me a comment that I can post anonymously or send an anonymous Surveymonkey, that would be great. My posts are generally written quickly, so if you find any factual or grammatical errors, please do let me know. Best regards, Philip Lederer

 

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