Whole-genome sequencing identifies nosocomial transmission of extra-pulmonary MTB

Hospital infection control practice reflects the working assumption that extra pulmonary TB is not considered infectious. A recent case report from Oxford, UK described how whole-genome sequencing identified the nosocomial transmission of extra-pulmonary MTB infection.

The patient had “an immune reconstitution like-syndrome with suppurating lymph nodes requiring daily dressing whilst remaining culture positive for 3 weeks.”

Aerosol generation during dressing changes was most likely the source of the TB transmission, given the less-than-impressive Chest CT scan.

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2 thoughts on “Whole-genome sequencing identifies nosocomial transmission of extra-pulmonary MTB

  1. Thank Philip for sharing.
    For us general conclusion is that not only airborne transmission precautions should be in place, but also the general IC ones. Contact TB transmission may probably occur from suppurative extrapulmonary TB patients.

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